Before Prohibition:
Images from the preprohibition era when many psychotropic substances 
were legally available in America and Europe

Background

Cocaine-Containing Products

Paperweight advertisement for C.F. Boehringer & Soehne (Mannheim, Germany), "largest makers in the world of quinine and cocaine." This chemical manufacturer was proud of its leading position in the world's cocaine market.

Cocaine-containing topical anesthetics

Cocaine toothache drops were popular with children and with their parents. Not only would the medicine numb the pain, but it could also put the user in a "better" mood.

Cocaine-containing throat lozenges, "indispensable for singers, teachers, and orators." In addition to quieting a sore throat, these lozenges undoubtedly provided the "pick-me-up" to keep these professionals performing at their peak. This box of lozenges is from a Belgium pharmacy (c. 1900). Local pharmacies often bought their drugs in bulk and packaged them for consumers under their own labels.

Cocaine-containing wines

Metcalf's Coca Wine was one of a large number of cocaine-containing wines available on the market. All claimed medicinal effects, although they were undoubtedly consumed for their "recreational" value as well.

Vin Mariani was the leading coca wine. This advertisement features an endorsement from Berthelier, a popular late 19th century actor. The caption immediately below the photograph reads, "Your marvelous Tonic needs certainly no further recommendation as everyone is familiar with it, and no one would be without it. I claim 'VIN MARIANI' can have no equal; it will live forever." The caption also proclaims "over 7,000 written endorsements from prominent physicians in Europe and America" and that the product has had acclaim for 30 years. (From Harper's Magazine, March, 1894.)

This coca wine was made by the Maltine Manufacturing Company (New York). The dosage indicated on the back of the bottle reads: "A wine glass full with, or immediately after, meals. Children in proportion." Malt extract was taken for its health-promoting effects and alcohol was considered by many to have medicinal effects. It's not surprising to see the 'virtues' of these three "medicines" combined into a single product.

In addition to curing the usual ailments coca wine was claimed to remedy, Bullard & Shedd's brand of coca wine claimed to be effective in curing sea sickness. It was also promoted to cure the "opium or alcohol habit."

Burnett's Cocoaine (c. 1880) contained coconut oil not cocaine as its primary ingredient. Hoping to capitalize on the popularity of products containing cocaine and their association with "modern medicine," some manufacturers developed similarly sounding proprietary names. Burnett's Cocoaine bottles are bought and sold by many modern collectors who mistakenly believe the product contained cocaine. They must be similarly confused about the nature of "cocoa" and "coca" products. ("Cocoanut" is also a variant spelling of "coconut," and hence the aptly named product.)

Opiate-Containing Products

Modern authors usually suggest that widespread opium use was a major health problem during the 19th century. However, the use of opiates must be kept in proper perspective with other contemporary health problems. Mortality from cholera, malaria, and dysentery was very high, and opiates provided some relief from these illnesses (Opiates remain the most effective treatment for dysentery.). Some authors have suggested that the easy availability of opiate-based medicines saved more lives than it took. As the deleterious effects of chronic opiate use became increasingly recognized during the late 19th century, several factors helped ease the need for opiates: the improvements in sanitation diminished cholera and dysentery, the drainage of swamp lands decreased malaria, and the introduction of acetylsalicylic acid (aspirin; 1899) provided an alternative medicine for moderate pain relief.

This bottle of Stickney and Poor's paregoric was distributed much like the spices for which the company is better known. McCormick also manufactured and sold paregoric, which is a mixture of opium and alcohol. Doses for infants, children, and adults are given on the bottle. At 46% alcohol, this product is 92 proof which is pretty potent in itself.

Heroin was commercially developed by Bayer Pharmaceutical and was marketed by Bayer and other companies (c. 1900) for several medicinal uses including cough suppression.

This magazine advertisement is for Glyco-Heroin manufactured by Martin H. Smith Company (New York). Heroin was widely used not only as an analgesic but also as a remedy for asthma, coughs, and pneumonia. Mixing heroin with glycerin (and often adding sugar or spices) made the bitter-tasting opiate more palatable for oral consumption. (From International Medical Magazine, January, 1902.)

These Heroin tablets manufactured by The Fraser Tablet Company were marketed for the relief of asthma.

This National Vaporizer Vapor-OL (opium) Treatment no. 6 for asthma may have provided a unique method of essentially "smoking" opium. The volatile liquid was placed in a pan that was heated by a small kerosene lamp (see below). Other substances were also used in these early (c. 1890) vaporizers, but this mixture probably ensured plenty of visitors for the spasmodically affected.

Vapo-cresolene lamps were marketed primarily to vaporize creosol-based products for the relief of head and chest congestion. However, they were also used with other products such as the opium-based asthma medicine shown above.

Mrs. Winslow's Soothing Syrup was an indispensable aid to mothers and child-care providers. Containing one grain (65 mg) of morphine per fluid ounce, it effectively quieted restless infants and small children. It probably also helped mothers relax after a hard day's work. The company used various media to promote their product, including recipe books, calendars, and trade cards such as the one shown here from 1887 (A calendar is on the reverse side.).

Opium smoking was another common method of administering opium. Although often associated with the Chinese, opium smoking was much more widespread and especially popular with some affluent occidentals. Various media, such as this postcard from San Francisco (c. 1900), encouraged the popular stereotype. In addition to the "recreational" effects produced by smoked opium, certain medicinal effects were also produced. These effects were similar to those produced by Glyco-heroin, paregoric, and other opiate-containing medications. (cf. Vapo-OL [opium] Treatment no. 6 for asthma illustrated above.)

Amphetamine-Containing Products

Benzedrine (racemic amphetamine) inhalers were available over-the-counter until the early 1950s. Some airlines even gave them out to passengers to minimize discomfort when the plane was landing and taking off. The Smith, Kline, and French advertisement proudly proclaims that over 10 million Benzedrine inhalers had been shipped by 1938, only 7 years after the product's introduction. This may have even outpaced McDonald's hamburger sales during their early expansion (Remember the "over x million hamburgers sold" signs on the golden arches?).

Common Formulations
for early psychoactive medicines